Depression has not responded. You still have options.
SPRAVATO® is an FDA-approved prescription nasal spray for eligible adults with treatment-resistant depression. At OHHW, treatment is delivered in a private, REMS-certified clinical setting with required monitoring and psychiatric oversight.
An evaluation is required. Insurance authorization and treatment approval are not guaranteed.
When standard antidepressants have not been enough
SPRAVATO® contains esketamine and works differently from traditional antidepressants. For treatment-resistant depression, it may be prescribed alone or with an oral antidepressant based on your clinical needs.
Persistent symptoms
You continue to experience depression despite appropriate medication trials and ongoing treatment.
Incomplete response
Past medications may have helped somewhat, but not enough to restore your functioning or quality of life.
Need for a new approach
You and your provider are considering an evidence-based option with a different mechanism of action.
Clear steps. Clinical oversight. No guessing.
Our team helps you understand what is required before treatment begins and what to expect at each stage.
Comprehensive evaluation
We review your diagnosis, symptoms, medication history, medical conditions, current medications and treatment goals.
Benefits and authorization review
When insurance is used, our team verifies benefits and submits required clinical documentation for prior authorization.
In-office treatment
You self-administer SPRAVATO® under direct observation in our certified healthcare setting.
Monitoring and follow-up
We monitor vital signs and clinical response, then reassess progress throughout your treatment course.
A calm setting with required safety monitoring
SPRAVATO® is not taken at home. Every dose is administered in the office and followed by clinical observation.
Prepare for your visit
Follow eating and drinking instructions, bring your medication information and arrange a ride home.
Self-administer in office
You use the nasal spray under direct observation. Blood pressure and overall condition are assessed.
Remain for monitoring
You stay for at least two hours and leave only after a healthcare professional determines you are clinically stable.
SPRAVATO® care that is part of a complete psychiatric plan
We do not treat SPRAVATO® as a stand-alone procedure. Your treatment is considered within the larger context of your symptoms, health history, current care and goals.
Whole-person assessment
Psychiatric and medical considerations are reviewed before treatment begins.
Direct provider oversight
Your response, tolerability and ongoing treatment needs are monitored by a psychiatric team.
Insurance coordination
We assist with benefits verification and prior authorization requirements when applicable.
Private local setting
Receive treatment at our Brandon office in a supportive, professional environment.
Using insurance?
Coverage and requirements vary by plan. Our team will review your benefits and explain the next steps before treatment is scheduled.
What patients usually want to know first
Is SPRAVATO® the same as IV ketamine?
No. SPRAVATO® contains esketamine and is an FDA-approved prescription nasal spray for specific depressive conditions. IV ketamine is a different treatment and is used off-label for depression.
How often is treatment given?
For treatment-resistant depression, the labeled schedule generally begins twice weekly for four weeks, then decreases based on response. Your actual schedule is individualized by your prescriber.
Can I drive myself home?
No. You must arrange transportation home after every treatment and should not drive or operate machinery until the next day after a restful sleep.
Will insurance cover SPRAVATO®?
Many plans cover SPRAVATO® for eligible patients, but most require prior authorization and documentation of previous treatments. Verification is not a guarantee of payment.
Will I feel better after the first treatment?
Responses vary. Some patients notice changes earlier, while others require multiple treatments before benefit can be assessed. Improvement cannot be promised.
Can SPRAVATO® be taken at home?
No. It must be administered in a certified healthcare setting under direct observation, followed by at least two hours of monitoring.
Find out whether SPRAVATO® may be appropriate for you.
Request a comprehensive evaluation with Oliphant Holistic Health & Wellness in Brandon, Florida. We will review your history, discuss risks and benefits, and explain the treatment and insurance process.
Important safety information
SPRAVATO® may cause serious side effects, including sedation, dissociation, respiratory depression, increased blood pressure, and abuse and misuse. Because of these risks, SPRAVATO® is available only through a restricted program called the SPRAVATO® REMS.
Patients must be monitored by a healthcare provider for at least two hours after each administration and must not drive, operate machinery or perform activities requiring complete alertness until the next day after a restful sleep. SPRAVATO® is not appropriate for everyone. A clinical evaluation is required.
SPRAVATO® has not been demonstrated to prevent suicide or reduce suicidal thoughts or behavior. OHHW's SPRAVATO® program is not an emergency service. In a psychiatric emergency, call 911, go to the nearest emergency department, or call or text 988.